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KMID : 0380020110260040277
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Korean Journal of Biotechnology and Bioengineering
2011 Volume.26 No. 4 p.277 ~ p.282
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A Study on Transdermal Drug Delivery System with Microneedle System in the Field of Skin Care
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Kim Sung-Jun
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Abstract
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The penetration of outside material into skin is not easy. It is since the skin, which is a very hard barrier, protects the body against outside chemical and physical stimulation. Microneedle system which can help improve drug penetration into skin is advancing variously in transdermal drug delivery system (TDDS) in the field of skin care. After inserting microneedle into skin by using electrical or artificial forces, it makes microhole and drug penetration easily and induces natural skin rejuvenation. Diffusion and penetration of drug by optical and electrical force of microneedle is better for fast and effective TDDS. This is more developed than the traditional method such as the manual stamp, roller, and meso gun. The drug absorbed into dermal layer by microneedle helps revive and repair damaged skin. In the future, utilization of microneedle for skin care will progress constantly because of its human-friendly biodegradable materials and the development of the no pain microneedle.
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KEYWORD
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Microneedle, transdermal drug delivery system (TDDS), skin barrier, skin rejuvenation, skin care
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